I’m definitely “extrapolating” the evidence almost 100% of the time when I use this, as it is almost never in the context of very recent ACS. And as noted, I never bother with simva anymore.
Still, I go to that before going to PCSK 9 mAb or siRNA due to cost.
Possibly pedantic but hopefully helpful spelling correction: “The trial has good interval validity” — I’m sure you meant “internal”.
I’m definitely “extrapolating” the evidence almost 100% of the time when I use this, as it is almost never in the context of very recent ACS. And as noted, I never bother with simva anymore.
Still, I go to that before going to PCSK 9 mAb or siRNA due to cost.